Sending Out an SOS: Mitochondria as a Signaling Hub

Sending Out an SOS: Mitochondria as a Signaling Hub

Normal cellular physiology is critically dependent on numerous mitochondrial activities including energy conversion, cofactor and precursor metabolite synthesis, and regulation of ion and redox homeostasis. Advances in mitochondrial research during the last two decades provide solid evidence that these organelles are deeply integrated with the rest of the cell and multiple mechanisms are in pla...

Timeline: Sending Out an SOS

A passage to India's HIV epidemics: sending out an SOS.

The official view is that India's epidemics are driven, directly and indirectly, by heterosexual prostitution. Review of available evidence by researchers in India undermines this weakly supported orthodoxy and suggests that correcting weaknesses in its AIDS surveillance system can lead to a more reliable picture of HIV propagation and hence to evidence-based interventions. Contenders for leadi...

Mitochondria: the hub of cellular Ca2+ signaling.

Mitochondria couple cellular metabolic state with Ca(2+) transport processes. They therefore control not only their own intra-organelle [Ca(2+)], but they also influence the entire cellular network of cellular Ca(2+) signaling, including the endoplasmic reticulum, the plasma membrane, and the nucleus. Through the detailed study of mitochondrial roles in Ca(2+) signaling, a remarkable picture of...

Smart City as an Smart Energy Hub: A Bibliographic, Analytic and Structural Review

Energy supply is one of the main challenges of the present century. Population growth, rising energy demand, fossil fuel scarcity, and environmental concerns have made energy security as major issue for all countries in the world. Traditional power system, including low-efficiency generation, long-distance transmission and then a complex distribution system, face various challenges that make it...